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Article

A Neutralizing Prolactin Receptor Antibody Whose In Vivo Application Mimics the Phenotype of Female Prolactin Receptor-Deficient Mice.

Endocrinology - 1 Nov 2015

Otto Christiane, Särnefält Anna, Ljungars Anne, Wolf Siegmund, Rohde-Schulz Beate, Fuchs Iris, Schkoldow Jenny, Mattsson Mikael, Vonk Richardus, Harrenga Axel, Freiberg Christoph

Abstract excerpt

The prolactin receptor (PRLR) has been implicated in a variety of physiological processes (lactation, reproduction) and diseases (breast cancer, autoimmune diseases). Prolactin synthesis in the pituitary and extrapituitary sites is regulated by different promoters. Dopamine receptor agonists such as bromocriptine can only interfere with pituitary prolactin synthesis and thus do not induce a complete blockade of...

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Identifiers

PMID: 26284426
DOI: 10.1210/en.2015-1277

Genes

PRLR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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