Article
Lack of association of endothelial nitric oxide synthase polymorphisms and migraine.
Headache - 1 Jul 2008
Toriello María, Oterino Agustín, Pascual Julio, Castillo Jesús, Colás Rafael, Alonso-Arranz Ana, Ruiz-Alegría Carlos, Quintela Estrella, Montón Fernando, Ruiz-Lavilla Nuria
Abstract excerpt
OBJECTIVE: The aim of this study was to evaluate if 2 functional endothelial nitric oxide synthase (eNOS) gene polymorphisms might be risk factors for migraine. BACKGROUND: Nitric oxide synthase promotes the synthesis of nitric oxide (NO). NO is a potent vasodilator and mediates several processes involved in migraine pathophysiology. Only one study has suggested an association with migraine with aura. METHODS: We...
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