Article
Feasibility of Rebiopsy in Non-Small Cell Lung Cancer Treated with Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors.
Internal medicine (Tokyo, Japan) - 1 Jan 2015
Hasegawa Takaaki, Sawa Toshiyuki, Futamura Yohei, Horiba Akane, Ishiguro Takashi, Marui Tsutomu, Yoshida Tsutomu
Abstract excerpt
OBJECTIVE: Analyses of tumor biopsy samples from non-small cell lung cancer patients with acquired epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI) resistance are expected to reveal the molecular mechanisms of resistance. However, due to limited tissue availability, performing such analyses can be challenging. We herein investigated the feasibility of tumor rebiopsy in this patient...
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