Article
The role of decidual natural killer cell-derived soluble factors in early pregnancy.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Nov 2021
Zhang Xueling, Li Yuye, Huang Chunyu, Liu Su, Chen Xian, Yu Shuyi, Diao Lianghui, Zeng Yong
Abstract excerpt
Decidual natural killer cells (dNK), the predominant decidual lymphocytes in early pregnancy, are primarily identified based on their CD56bright CD16- phenotype and play an important role in maintaining immune tolerance at the maternal-fetal interface. dNK dysfunction reportedly leads to pathological pregnancy. Indeed, various dNK-derived soluble factors are involved in a series of key processes related to...
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