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Article

Analysis of B-Raf[Formula: see text] inhibitors using 2D and 3D-QSAR, molecular docking and pharmacophore studies.

Molecular diversity - 1 Nov 2015

Aalizadeh Reza, Pourbasheer Eslam, Ganjali Mohammad Reza

Abstract excerpt

In the present work, a molecular modeling study was carried out using 2D and 3D quantitative structure-activity relationships for the various series of compounds known as B-Raf[Formula: see text] inhibitors. For 2D-QSAR analysis, a linear model was developed by MLR based on GA-OLS with appropriate results [Formula: see text], which was validated by several external validation techniques. To perform a 3D-QSAR...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26276566
DOI: 10.1007/s11030-015-9626-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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