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Derivation of Adult Human Fibroblasts and their Direct Conversion into Expandable Neural Progenitor Cells

29 Jul 2015

Abstract excerpt

Generation of induced pluripotent stem cell (iPSCs) from adult skin fibroblasts and subsequent differentiation into somatic cells provides fascinating prospects for the derivation of autologous transplants that circumvent histocompatibility barriers. However, progression through a pluripotent state and subsequent complete differentiation into desired lineages remains a roadblock for the clinical translation of...

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PMID: 26275015
DOI: 10.3791/52831

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