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Article

Genetic Factors in the Pathogenesis of Nonalcoholic Fatty Liver and Steatohepatitis.

BioMed research international - 1 Jan 2015

Dongiovanni Paola, Romeo Stefano, Valenti Luca

Abstract excerpt

Liver fat accumulation generally related to systemic insulin resistance characterizes nonalcoholic fatty liver disease (NAFLD), which in the presence of nonalcoholic steatohepatitis (NASH) can progress towards cirrhosis and hepatocellular carcinoma. Due to the epidemic of obesity, NAFLD is now the most frequent liver disease in Western countries. Epidemiological, familial, and twin studies provide evidence for a...

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Source

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Identifiers

PMID: 26273621
DOI: 10.1155/2015/460190
PMCID: PMC4530215

Genes

PNPLA3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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