Article
Direct intercellular communications dominate the interaction between adipose-derived MSCs and myofibroblasts against cardiac fibrosis.
Protein & cell - 1 Oct 2015
Li Xiaokang, Zhao Hui, Qi Chunxiao, Zeng Yang, Xu Feng, Du Yanan
Abstract excerpt
The onset of cardiac fibrosis post myocardial infarction greatly impairs the function of heart. Recent advances of cell transplantation showed great benefits to restore myocardial function, among which the mesenchymal stem cells (MSCs) has gained much attention. However, the underlying cellular mechanisms of MSC therapy are still not fully understood. Although paracrine effects of MSCs on residual cardiomyocytes...
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