Article
Heart failure therapy mediated by the trophic activities of bone marrow mesenchymal stem cells: a noninvasive therapeutic regimen.
American journal of physiology. Heart and circulatory physiology - 1 Jun 2009
Shabbir Arsalan, Zisa David, Suzuki Gen, Lee Techung
Abstract excerpt
Heart failure carries a poor prognosis with few treatment options. While myocardial stem cell therapeutic trials have traditionally relied on intracoronary infusion or intramyocardial injection routes, these cell delivery methods are invasive and can introduce harmful scar tissue, arrhythmia, calcification, or microinfarction in the heart. Given that patients with heart failure are at an increased surgical risk,...
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