Article
The genomic and phenotypic diversity of Schizosaccharomyces pombe.
Nature genetics - 1 Mar 2015
Jeffares Daniel C, Rallis Charalampos, Rieux Adrien, Speed Doug, Převorovský Martin, Mourier Tobias, Marsellach Francesc X, Iqbal Zamin, Lau Winston, Cheng Tammy M K, Pracana Rodrigo, Mülleder Michael, Lawson Jonathan L D, Chessel Anatole, Bala Sendu, Hellenthal Garrett, O'Fallon Brendan, Keane Thomas, Simpson Jared T, Bischof Leanne, Tomiczek Bartlomiej, Bitton Danny A, Sideri Theodora, Codlin Sandra, Hellberg Josephine E E U, van Trigt Laurent, Jeffery Linda, Li Juan-Juan, Atkinson Sophie, Thodberg Malte, Febrer Melanie, McLay Kirsten, Drou Nizar, Brown William, Hayles Jacqueline, Carazo Salas Rafael E, Ralser Markus, Maniatis Nikolas, Balding David J, Balloux Francois, Durbin Richard, Bähler Jürg
Abstract excerpt
Natural variation within species reveals aspects of genome evolution and function. The fission yeast Schizosaccharomyces pombe is an important model for eukaryotic biology, but researchers typically use one standard laboratory strain. To extend the usefulness of this model, we surveyed the genomic and phenotypic variation in 161 natural isolates. We sequenced the genomes of all strains, finding moderate genetic...
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