Article
[The role of ATM kinase in neurodegeneration].
Postepy biochemii - 1 Jan 2014
Chwastek Jakub, Jantas Danuta, Lasoń Władysław
Abstract excerpt
Neurodegenerative diseases represent a major challenge for modern medicine. Despite many years of research, no effective neuroprotective therapy has been proposed. Ataxia telangiectasia (A-T) is rare disease, which is caused by a mutation of the ATM protein. Cerebellar degeneration is the main symptom of the A-T. The kinase ATM, inter alia is involved in the repair of DNA damage, cell cycle regulation and the...
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