Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel Method Probe-based Real-Time PCR to Detect 2 Single-Nucleotide Polymorphisms Close to Each Other: HFE Hemochromatosis Gene Model.

Applied immunohistochemistry & molecular morphology : AIMM - 1 Oct 2016

Malta Frederico S V, Reis Zilma N, Cabral Antônio C V

Abstract excerpt

Hereditary hemochromatosis is known as the most common genetic disorder among individuals of European genetic background. It is possible to find 2 mutations closely placed in the HFE gene (H63D and S65C) and this proximity can cause errors when genotyped by real-time polymerase chain reaction (PC...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Probes
Share to HFE gene
Share to Hemochromatosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hemochromatosis Protein

Share to Polymorphism, Single Nucleotide

Share to Real-Time Polymerase Chain Reaction

Share to Reproducibility of Results

Source

Identifiers

PMID: 26258758
DOI: 10.1097/PAI.0000000000000206

Genes

HFE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26258758-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel Method Probe-based Real-Time PCR to Detect 2 Single-Nucleotide Polymorphisms Close to Each Other: HFE Hemochromatosis Gene Model.PMID 26258758Read ↗

Improved real-time detection of the H63D and S65C mutations associated with hereditary hemochromatosis using a SimpleProbe assay format.Semantic proximity Read ↗

Genotyping of hemochromatosis-associated mutations in the HFE gene by PCR-RFLP and a novel reverse hybridization method.Semantic proximity Read ↗

Detection of the C282Y and H63D polymorphisms associated with hereditary hemochromatosis using the ABI 7500 fast real time PCR platform.Semantic proximity Read ↗

Simultaneous detection of HFE C282Y, H63D and S65C mutations associated with type 1 haemochromatosis using a multiplex luminex bead assay.Semantic proximity Read ↗

Frequency of common HFE variants in the Saudi population: a high throughput molecular beacon-based study.Semantic proximity Read ↗

[Methods for detecting single nucleotide polymorphisms: allele-specific PCR and hybridization with oligonucleotide probe].Semantic proximity Read ↗

Rapid detection of genetic mutations associated with haemochromatosis.Semantic proximity Read ↗

Single nucleotide polymorphism genotyping of ALDH2 gene based on asymmetric PCR and fluorescent probe-mediated melting curves.Semantic proximity Read ↗

Real-time PCR genotyping using displacing probes.Semantic proximity Read ↗

Fluorescent multicolor multiplex homogeneous assay for the simultaneous analysis of the two most common hemochromatosis mutations.Semantic proximity Read ↗

Design and validation of a colorimetric test for the genetic diagnosis of hemochromatosis using α-phosphorothioate nucleotides.Semantic proximity Read ↗

Screening, Confirmation and Validation of Mismatch AS F-Primers for Hypertension-Related Genotyping.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.