Article
Frequency of common HFE variants in the Saudi population: a high throughput molecular beacon-based study.
BMC medical genetics - 3 May 2006
Alsmadi Osama A, Al-Kayal Fadi, Al-Hamed Mohamed, Meyer Brian F
Abstract excerpt
BACKGROUND: Hereditary Hemochromatosis (HH) is an autosomal recessive disorder highlighted by iron-overload. Two popular mutations in HFE, p.C282Y and p.H63D, have been discovered and found to associate with HH in different ethnic backgrounds. p.C282Y and p.H63D diagnosis is usually made by restriction enzyme analysis. However, the use of this technique is largely limited to research laboratories because they are...
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