Article
Rapid detection of genetic mutations associated with haemochromatosis.
Vox sanguinis - 1 Jan 1998
Guttridge M G, Thompson J, Worwood M, Darke C
Abstract excerpt
BACKGROUND AND OBJECTIVES: The purpose of this study was to establish a rapid method suitable for large-scale population screening, including blood donors, for the detection of two genetic mutations at codons 63 and 282 on the HFE gene that are associated with haemochromatosis. MATERIALS AND METH...
Topics
- Alleles
- Amino Acid Substitution
- DNA Mutational Analysis
- Genetic Testing
- Genotype
- Hemochromatosis
- Humans
- Mutation, Missense
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Single-Blind Method
- Time Factors