Article
[ROS1-Translocations in Non-Small Cell Lung Cancer].
Pneumologie (Stuttgart, Germany) - 1 Aug 2015
Warth A, Weichert W, Reck M, Reinmuth N
Abstract excerpt
AIM: Summary of prevalence, testing and treatment approaches in patients with non-small cell lung cancer (NSCLC) and ROS1 activation. METHODS: Internet-based search for clinical and preclinical studies as well as search for ongoing studies in web-based databases. RESULTS: ROS1 translocations lead to tyrosine kinase activation and can be detected in 1 - 2% of all NSCLC and in 3 - 6% of pulmonary adenocarcinoma...
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