Article
Human papillomavirus infection and p16 overexpression in oropharyngeal squamous cell carcinoma: a case series from 2010 to 2014.
Future microbiology - 1 Jan 2015
Donà Maria Gabriella, Spriano Giuseppe, Pichi Barbara, Rollo Francesca, Laquintana Valentina, Covello Renato, Pellini Raul, Giuliani Massimo, Pescarmona Edoardo, Benevolo Maria
Abstract excerpt
AIM: Human papillomavirus (HPV) associated oropharyngeal squamous cell carcinomas (OPSCC) show better prognosis and response to therapy. We evaluated HPV-DNA prevalence, p16 overexpression and HPV-attributable fraction in recent consecutive OPSCCs. MATERIALS & METHODS: 140 OPSCCs were analyzed for HPV-DNA using the INNO-LiPA assay and p16 overexpression using CINtec® Histology kit. RESULTS: HPV-DNA prevalence was...
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