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Virology and molecular pathogenesis of HPV (human papillomavirus)associated oropharyngeal squamous cell carcinoma

27 Mar 2012

Abstract excerpt

The current literature fully supports HPV (human papillomavirus)-associated OPSCC (oropharyngeal squamous cell carcinoma) as a unique clinical entity. It affects an unambiguous patient population with defined risk factors, has a genetic expression pattern more similar to cervical squamous cell carcinoma than non-HPV-associated HNSCC (head and neck squamous cell carcinoma), and may warrant divergent clinical...

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PMID: 22452816
DOI: 10.1042/bj20112017

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