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The Role of Methylation in Breast Cancer Susceptibility and Treatment.

Anticancer research - 1 Sept 2015

Pouliot Marie-Christine, Labrie Yvan, Diorio Caroline, Durocher Francine

Abstract excerpt

DNA methylation is a critical mechanism of epigenetic modification involved in gene expression programming, that can promote the development of several cancers, including breast cancer. The methylation of CpG islands by DNA methyltransferases is reversible and has been shown to modify the transcriptional activity of key proliferation genes or transcription factors involved in suppression or promotion of cell...

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PMID: 26254344

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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