Impact of VEGF, VEGFR, PDGFR, HIF and ERCC1 gene polymorphisms on thymic malignancies outcome after thymectomy.

doi:10.18632/oncotarget.4191

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Article

Impact of VEGF, VEGFR, PDGFR, HIF and ERCC1 gene polymorphisms on thymic malignancies outcome after thymectomy.

Oncotarget - 7 Aug 2015

Berardi Rossana, Brunelli Alessandro, Pagliaretta Silvia, Paolucci Vittorio, Conti Alessandro, Goteri Gaia, Refai Majed, Pompili Cecilia, Marcantognini Giulia, Morgese Francesca, Ballatore Zelmira, Savini Agnese, De Lisa Mariagrazia, Caramanti Miriam, Santoni Matteo, Zizzi Antonio, Piva Francesco, Mazzanti Paola, Onofri Azzurra, Sabbatini Armando, Scarpelli Marina, Cascinu Stefano

Abstract excerpt

We aimed to analyze genotypes of VEGF-A, VEGFR2, Flt4, PDGFRα, HIF-1α and ERCC1 and their correlation with thymic tumor risk and patient outcome. DNA of 57 consecutive patients (43 thymomas and 14 thymic carcinomas) who underwent total thymectomy at our Institution was extracted from paraffin-embedded tissue. We selected polymorphisms in the following genes:HIF1-α (rs2057482T > C, rs1951795A > C, rs2301113C > A,...

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PMID: 26254278
DOI: 10.18632/oncotarget.4191
PMCID: PMC4662492

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ERCC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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