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Article

Lymphatic MAFB regulates vascular patterning during developmental and pathological lymphangiogenesis

19 Apr 2020

Abstract excerpt

MAFB is a transcription factor involved in the terminal differentiation of several cell types, including macrophages and keratinocytes. MAFB is also expressed in lymphatic endothelial cells (LECs) and is upregulated by VEGF-C/VEGFR-3 signaling. Recent studies have revealed that MAFB regulates several genes involved in lymphatic differentiation and that global Mafb knockout mice show defects in patterning of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32307629
DOI: 10.1007/s10456-020-09721-1

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