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Article

Regulation of Gonad Morphogenesis in Drosophila melanogaster by BTB Family Transcription Factors.

PloS one - 1 Jan 2016

Silva Diane, Olsen Kenneth W, Bednarz Magdalena N, Droste Andrew, Lenkeit Christopher P, Chaharbakhshi Edwin, Temple-Wood Emily R, Jemc Jennifer C

Abstract excerpt

During embryogenesis, primordial germ cells (PGCs) and somatic gonadal precursor cells (SGPs) migrate and coalesce to form the early gonad. A failure of the PGCs and SGPs to form a gonad with the proper architecture not only affects germ cell development, but can also lead to infertility. Therefore, it is critical to identify the molecular mechanisms that function within both the PGCs and SGPs to promote gonad...

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Identifiers

PMID: 27898696
DOI: 10.1371/journal.pone.0167283
PMCID: PMC5127561

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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