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Article

Identification of a blood-borne miRNA signature of synovial sarcoma

6 Aug 2015

Abstract excerpt

BACKGROUND: Synovial sarcoma account for approximately 10 % of all soft-tissue tumors and occur most frequently in young adults. A specific translocation in this sarcoma induces fusion of the SYT gene on chromosome 18 to the SSX genes on chromosome X, leading to proliferation of the tumor cells. The need for non-invasive biomarkers indicating recurrence and activity of this disease has sparked research into short...

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PMID: 26250552
DOI: 10.1186/s12943-015-0424-z

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