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The Double Life of microRNAs in Bone Sarcomas: Oncogenic Drivers and Tumor Suppressors

17 May 2025

Abstract excerpt

Bone sarcomas, including Osteosarcoma, Ewing's sarcoma, and Chondrosarcoma, are rare yet aggressive tumors with high metastatic potential and poor survival outcomes. Despite advances in surgical and chemotherapeutic techniques, these malignancies remain difficult to treat. They often exhibit resistance to conventional therapies and are associated with a limited prognosis for patients. MicroRNAs (miRNAs) have...

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PMID: 40429954
DOI: 10.3390/ijms26104814

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