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Mechanisms and strategies of papillomavirus replication

18 Mar 2017

Abstract excerpt

Animal and human papillomaviruses (HPVs) replicate persistently in specific types of stratified epithelia of their host. After the initial infection, the viral genome replicates at low levels in the dividing cells of the epithelium, and these cells form a reservoir of infection that can last for decades. When the infected cells differentiate, viral genomes replicate to high levels to form progeny virus that is...

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PMID: 28315855
DOI: 10.1515/hsz-2017-0113

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