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Protective Enterotoxigenic Escherichia coli Antigens in a Murine Intranasal Challenge Model

5 Aug 2015

Abstract excerpt

Enterotoxigenic Escherichia coli (ETEC) is an endemic health threat in underdeveloped nations. Despite the significant effort extended to vaccine trials using ETEC colonization factors, these approaches have generally not been especially effective in mediating cross-protective immunity. We used quantitative proteomics to identify 24 proteins that differed in abundance in membrane protein preparations derived from...

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PMID: 26244636
DOI: 10.1371/journal.pntd.0003924

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