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Article

Conservation and global distribution of non-canonical antigens in Enterotoxigenic Escherichia coli.

PLoS neglected tropical diseases - 1 Nov 2019

Kuhlmann F Matthew, Martin John, Hazen Tracy H, Vickers Tim J, Pashos Madeline, Okhuysen Pablo C, Gómez-Duarte Oscar G, Cebelinski Elizabeth, Boxrud Dave, Del Canto Felipe, Vidal Roberto, Qadri Firdausi, Mitreva Makedonka, Rasko David A, Fleckenstein James M

Abstract excerpt

BACKGROUND: Enterotoxigenic Escherichia coli (ETEC) cause significant diarrheal morbidity and mortality in children of resource-limited regions, warranting development of effective vaccine strategies. Genetic diversity of the ETEC pathovar has impeded development of broadly protective vaccines centered on the classical canonical antigens, the colonization factors and heat-labile toxin. Two non-canonical ETEC...

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Identifiers

PMID: 31756188
DOI: 10.1371/journal.pntd.0007825
PMCID: PMC6897418

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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