Article
Disentangling the impact of within-host evolution and transmission dynamics on the tempo of HIV-1 evolution.
AIDS (London, England) - 31 Jul 2015
Vrancken Bram, Baele Guy, Vandamme Anne-Mieke, van Laethem Kristel, Suchard Marc A, Lemey Philippe
Abstract excerpt
OBJECTIVE: To determine how HIV-1 risk groups impact transmitted diversity and the tempo of viral evolution at a population scale. METHODS: We investigated a set of previously described transmission chains (n = 70) using a population genetic approach, and tested whether the expected differences in proportions of multivariant transmissions are reflected by varying proportions of transmitted diversity between men...
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