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Article

A Novel WRN Frameshift Mutation Identified by Multiplex Genetic Testing in a Family with Multiple Cases of Cancer.

PloS one - 1 Jan 2015

Yang Liu, Wang Guosheng, Zhao Xinyi, Ye Song, Shen Peng, Wang Weilin, Zheng Shusen

Abstract excerpt

Next-generation sequencing technology allows simultaneous analysis of multiple susceptibility genes for clinical cancer genetics. In this study, multiplex genetic testing was conducted in a Chinese family with multiple cases of cancer to determine the variations in cancer predisposition genes. The family comprises a mother and her five daughters, of whom the mother and the eldest daughter have cancer and the...

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Source

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Identifiers

PMID: 26241669
DOI: 10.1371/journal.pone.0133020
PMCID: PMC4524609

Genes

WRN
ELAC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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