Case Report: A novel WRN mutation in Werner syndrome patient with diabetic foot disease and myelodysplastic syndrome.

Abstract excerpt

Werner syndrome is an autosomal recessive rare disease caused by a WRN gene mutation, which is rarely reported in the Chinese population. We report the clinical and genetic data of a Chinese patient with Werner syndrome. The proband was a 40-year-old male patient who presented with diabetic foot ulcers, accompanied by short stature, cataracts, hypogonadism, and hair thinning, and myelodysplastic syndrome (MDS)...

Topics

• Adult
• Diabetes Mellitus
• Diabetic Foot
• Humans
• Male
• Mutation
• Myelodysplastic Syndromes
• Werner Syndrome
• Werner Syndrome Helicase