Article
Structure-function discrepancy in Clostridium botulinum C3 toxin for its rational prioritization as a subunit vaccine.
Journal of biomolecular structure & dynamics - 1 Jun 2016
Prathiviraj R, Prisilla A, Chellapandi P
Abstract excerpt
Clostridium botulinum is anaerobic pathogenic bacterium causing food-born botulism in human and animals by producing botulinum neurotoxins A-H, C2, and C3 cytotoxins. Physiological group III strains (type C and D) of this bacterium are capable of producing C2 and C3 toxins in cattle and avian. Herein, we have revealed the structure-function disparity of C3 toxins from two different C. botulinum type C phage...
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