Article
MicroRNA deregulation in symptomatic carotid plaque.
Journal of vascular surgery - 1 Nov 2015
Maitrias Pierre, Metzinger-Le Meuth Valérie, Massy Ziad A, M'Baya-Moutoula Eléonore, Reix Thierry, Caus Thierry, Metzinger Laurent
Abstract excerpt
OBJECTIVE: Embolization of carotid stenotic plaques is the direct cause of stroke in nearly 20% of cases. Genetic mechanisms and especially the roles played by microRNAs in the regulation of plaque destabilization and rupture are mostly unknown. The aim of this pilot study was to compare the expression of seven microRNAs allegedly involved in plaque growth and instability (miR-100, 125a, 127, 133a, 145, 155, and...
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