Article
Estimating allele dropout probabilities by logistic regression: Assessments using Applied Biosystems 3500xL and 3130xl Genetic Analyzers with various commercially available human identification kits.
Legal medicine (Tokyo, Japan) - 1 Mar 2016
Inokuchi Shota, Kitayama Tetsushi, Fujii Koji, Nakahara Hiroaki, Nakanishi Hiroaki, Saito Kazuyuki, Mizuno Natsuko, Sekiguchi Kazumasa
Abstract excerpt
Phenomena called allele dropouts are often observed in crime stain profiles. Allele dropouts are generated because one of a pair of heterozygous alleles is underrepresented by stochastic influences and is indicated by a low peak detection threshold. Therefore, it is important that such risks are statistically evaluated. In recent years, attempts to interpret allele dropout probabilities by logistic regression...
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