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Allelic drop-out probabilities estimated by logistic regression--further considerations and practical implementation.

Forensic science international. Genetics - 1 Mar 2012

Tvedebrink Torben, Eriksen Poul Svante, Asplund Maria, Mogensen Helle Smidt, Morling Niels

Abstract excerpt

We discuss the model for estimating drop-out probabilities presented by Tvedebrink et al. [7] and the concerns, that have been raised. The criticism of the model has demonstrated that the model is not perfect. However, the model is very useful for advanced forensic genetic work, where allelic drop-out is occurring. With this discussion, we hope to improve the drop-out model, so that it can be used for practical...

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PMID: 21733771
DOI: 10.1016/j.fsigen.2011.06.004

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