Distinguishing between donors and their relatives in complex DNA mixtures with binary models.

doi:10.1016/j.fsigen.2015.12.001

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Article

Distinguishing between donors and their relatives in complex DNA mixtures with binary models.

Forensic science international. Genetics - 1 Mar 2016

Slooten K

Abstract excerpt

While likelihood ratio calculations were until the recent past limited to the evaluation of mixtures in which all alleles of all donors are present in the DNA mixture profile, more recent methods are able to deal with allelic dropout and drop-in. This opens up the possibility to obtain likelihood ratios for mixtures where this was not previously possible, but it also means that a full match between the alleged...

Topics

Alleles
Complex Mixtures
DNA
DNA Fingerprinting
Family
Forensic Genetics
Humans
Likelihood Functions
Microsatellite Repeats
Models, Genetic
Models, Statistical
Sequence Analysis, DNA

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Open in PubMed

Identifiers

PMID: 26745184
DOI: 10.1016/j.fsigen.2015.12.001

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