Article
4-Acetylantroquinonol B inhibits colorectal cancer tumorigenesis and suppresses cancer stem-like phenotype.
Toxicology and applied pharmacology - 15 Oct 2015
Chang Tung-Cheng, Yeh Chi-Tai, Adebayo Bamodu Oluwaseun, Lin Ying-Chin, Deng Li, Rao Yerra Koteswara, Huang Chun-Chih, Lee Wei-Hwa, Wu Alexander T H, Hsiao Michael, Wu Chih-Hsiung, Wang Liang-Shun, Tzeng Yew-Min
Abstract excerpt
4-Acetylantroquinonol B (4-AAQB), closely related to the better known antroquinonol, is a bioactive isolate of the mycelia of Antrodia camphorata, a Taiwanese mushroom with documented anti-inflammatory, hypoglycemic, vasorelaxative, and recently demonstrated, antiproliferative activity. Based on its traditional use, we hypothesized that 4-AAQB may play an active role in the suppression of cellular transformation,...
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