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Gambogic acid inhibits growth, induces apoptosis, and overcomes drug resistance in human colorectal cancer cells

15 Sept 2015

Abstract excerpt

The emergence of chemoresistance is a major limitation of colorectal cancer (CRC) therapies and novel biologically based therapies are urgently needed. Natural products represent a novel potential anticancer therapy. Gambogic acid (GA), a small molecule derived from Garcinia hanburyi Hook. f., has been demonstrated to be highly cytotoxic to several types of cancer cells and have low toxicity to the hematopoietic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26397804
DOI: 10.3892/ijo.2015.3166

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