Article
Antisense Therapy for Cardiovascular Diseases.
Current pharmaceutical design - 1 Jan 2015
Phillips M Ian, Costales Jessica, Lee Robert J, Oliveira Edilamar, Burns Andrew B
Abstract excerpt
Antisense oligonucleotide therapy is a growing field in cardiac, metabolic, and muscular diseases. This precision therapy allows for treatment of diseases due to specific genetic defects. Antisense has few side effects and is relatively long lasting. Some major targets for antisense therapy include hyperglycemia, hyperlipidemia, and hypercholesterolemia. ISIS Pharmaceuticals recently commercialized antisense...
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