Article
Comparative analysis between saliva and buccal swabs as source of DNA: lesson from HLA-B*57:01 testing.
Pharmacogenomics - 1 Jan 2015
Cascella Raffaella, Stocchi Laura, Strafella Claudia, Mezzaroma Ivano, Mannazzu Marco, Vullo Vincenzo, Montella Francesco, Parruti Giustino, Borgiani Paola, Sangiuolo Federica, Novelli Giuseppe, Pirazzoli Antonella, Zampatti Stefania, Giardina Emiliano
Abstract excerpt
AIM: Our work aimed to designate the optimal DNA source for pharmacogenetic assays, such as the screening for HLA-B*57:01 allele. MATERIALS & METHODS: A saliva and four buccal swab samples were taken from 104 patients. All the samples were stored at different time and temperature conditions and then genotyped for the HLA-B*57:01 allele by SSP-PCR and classical/capillary electrophoresis. RESULTS: The genotyping...
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