Article
Relationship between UGT1A1*6/*28 polymorphisms and severe toxicities in Chinese patients with pancreatic or biliary tract cancer treated with irinotecan-containing regimens.
Drug design, development and therapy - 1 Jan 2015
Yang Chen, Liu Ying, Xi Wen-qi, Zhou Chen-fei, Jiang Jin-ling, Ma Tao, Ye Zheng-bao, Zhang Jun, Zhu Zheng-gang
Abstract excerpt
PURPOSE: The aim of this retrospective study was to investigate the relationship between UGT1A1 polymorphisms and toxicities in Chinese patients with pancreatic or biliary tract cancer receiving irinotecan-containing regimens as the second- or third-line chemotherapy. PATIENTS AND METHODS: A total of 36 patients with unresectable pancreatic cancer and 12 patients with unresectable biliary tract cancer were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.