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Article

Influence of an Allergen-Specific Th17 Response on Remodeling of the Airways.

American journal of respiratory cell and molecular biology - 1 Mar 2016

Peters Marcus, Köhler-Bachmann Stefanie, Lenz-Habijan Tim, Bufe Albrecht

Abstract excerpt

We showed previously that sensitization of mice with dendritic cells (DCs) via the airways depends on activation of these cells with LPS. Allergen-pulsed DCs that were stimulated with low doses of LPS induce a strong Th2 response in vivo. Our objective was to investigate whether airway sensitization of mice by the application of DCs with a phenotype that is able to induce Th17 cells results in increased...

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PMID: 26222011
DOI: 10.1165/rcmb.2014-0429OC

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