Article
Tracking a hospital outbreak of carbapenem-resistant Klebsiella pneumoniae with whole-genome sequencing.
Science translational medicine - 22 Aug 2012
Snitkin Evan S, Zelazny Adrian M, Thomas Pamela J, Stock Frida, Henderson David K, Palmore Tara N, Segre Julia A
Abstract excerpt
The Gram-negative bacteria Klebsiella pneumoniae is a major cause of nosocomial infections, primarily among immunocompromised patients. The emergence of strains resistant to carbapenems has left few treatment options, making infection containment critical. In 2011, the U.S. National Institutes of Health Clinical Center experienced an outbreak of carbapenem-resistant K. pneumoniae that affected 18 patients, 11 of...
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