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Genomic epidemiology of global Klebsiella pneumoniae carbapenemase (KPC)-producing Escherichia coli

13 Jul 2017

Abstract excerpt

Abstract The dissemination of carbapenem resistance in Escherichia coli has major implications for the management of common infections. bla KPC , encoding a transmissible carbapenemase (KPC), has historically largely been associated with Klebsiella pneumoniae , a predominant plasmid (pKpQIL), and a specific transposable element (Tn 4401 , ~10 kb). Here we characterize the genetic features of bla KPC emergence in...

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PMID: 28725045
DOI: 10.1038/s41598-017-06256-2

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