Interaction between arsenic exposure from drinking water and genetic polymorphisms on cardiovascular disease in Bangladesh: a prospective case-cohort study.

doi:10.1289/ehp.1307883

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Article

Interaction between arsenic exposure from drinking water and genetic polymorphisms on cardiovascular disease in Bangladesh: a prospective case-cohort study.

Environmental health perspectives - 1 May 2015

Wu Fen, Jasmine Farzana, Kibriya Muhammad G, Liu Mengling, Cheng Xin, Parvez Faruque, Islam Tariqul, Ahmed Alauddin, Rakibuz-Zaman Muhammad, Jiang Jieying, Roy Shantanu, Paul-Brutus Rachelle, Slavkovich Vesna, Islam Tariqul, Levy Diane, VanderWeele Tyler J, Pierce Brandon L, Graziano Joseph H, Ahsan Habibul, Chen Yu

Abstract excerpt

BACKGROUND: Epidemiologic data on genetic susceptibility to cardiovascular effects of arsenic exposure from drinking water are limited. OBJECTIVE: We investigated whether the association between well-water arsenic and cardiovascular disease (CVD) differed by 170 single nucleotide polymorphisms (SNPs) in 17 genes related to arsenic metabolism, oxidative stress, inflammation, and endothelial dysfunction. METHOD: We...

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PMID: 25575156
DOI: 10.1289/ehp.1307883
PMCID: PMC4421763

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ICAM1
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