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The Flagellar Arginine Kinase in Trypanosoma brucei Is Important for Infection in Tsetse Flies

28 Jul 2015

Abstract excerpt

African trypanosomes are flagellated parasites that cause sleeping sickness. Parasites are transmitted from one mammalian host to another by the bite of a tsetse fly. Trypanosoma brucei possesses three different genes for arginine kinase (AK) including one (AK3) that encodes a protein localised to the flagellum. AK3 is characterised by the presence of a unique amino-terminal insertion that specifies flagellar...

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PMID: 26218532
DOI: 10.1371/journal.pone.0133676

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