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Article

Mechanistic study of intertypic nucleoprotein complex formation and its inhibitory effect toward influenza A virus.

Virology - 1 Nov 2015

Narkpuk Jaraspim, Jaru-Ampornpan Peera, Subali Theressa, Bertulfo Fatima Carla T, Wongthida Phonphimon, Jongkaewwattana Anan

Abstract excerpt

Co-infection of influenza A and B viruses (IAV and IBV) results in marked decreases in IAV replication. Multiple mechanisms have been proposed for this phenomenon. Recently, we reported that IBV nucleoprotein (BNP) alone can suppress IAV replication and proposed an inhibition model in which BNP binds IAV nucleoprotein (ANP) and disrupts IAV polymerase complexes. Here, using mutagenesis and co-immunoprecipitation,...

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PMID: 26218215
DOI: 10.1016/j.virol.2015.06.032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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