Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus.

doi:10.1073/pnas.1510199112

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Article

Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus.

Proceedings of the National Academy of Sciences of the United States of America - 18 Aug 2015

Corti Davide, Zhao Jincun, Pedotti Mattia, Simonelli Luca, Agnihothram Sudhakar, Fett Craig, Fernandez-Rodriguez Blanca, Foglierini Mathilde, Agatic Gloria, Vanzetta Fabrizia, Gopal Robin, Langrish Christopher J, Barrett Nicholas A, Sallusto Federica, Baric Ralph S, Varani Luca, Zambon Maria, Perlman Stanley, Lanzavecchia Antonio

Abstract excerpt

Middle East Respiratory Syndrome (MERS) is a highly lethal pulmonary infection caused by a previously unidentified coronavirus (CoV), likely transmitted to humans by infected camels. There is no licensed vaccine or antiviral for MERS, therefore new prophylactic and therapeutic strategies to combat human infections are needed. In this study, we describe, for the first time, to our knowledge, the isolation of a...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 26216974
DOI: 10.1073/pnas.1510199112
PMCID: PMC4547275

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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