Article
The Immunogenetics of Psoriasis.
Advances in experimental medicine and biology - 1 Jan 2022
Trovato Emanuele, Rubegni Pietro, Cinotti Elisa
Abstract excerpt
Psoriasis vulgaris is a chronic immune-mediated dermatological condition, resulting from an interaction between environmental triggers and genetic susceptibilities. Alteration in the production of the inflammatory mediators plays a pivotal part in the pathogenesis of the disease. Genes encoding the mediators of these inflammatory pathways can dictate susceptibility to psoriasis. These genes have a wide range of...
Topics
- CARD Signaling Adaptor Proteins
- Genetic Predisposition to Disease
- Guanylate Cyclase
- Humans
- Immunity, Innate
- Immunogenetics
- Interleukins
- Membrane Proteins
- Psoriasis
- Skin
