Article
[Relationship of Ghrelin gene polymorphism with congenital anorectal malformation and Hirschsprung disease].
Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery - 1 Jul 2015
Gao Hong, Wang Dajia, Zhao Xiangxuan, Mi Jie, Bai Yuzuo, Wang Weilin
Abstract excerpt
OBJECTIVE: To explore the relationship of Ghrelin gene polymorphism with the occurrence of human anorectal malformations (ARMs) and Hirschsprung disease(HSCR). METHODS: PCR and DNA sequencing were used to detect the single nucleotide polymorphism (SNPs) of 3 loci (rs139684563, rs149447194, rs186599567) genotype of Ghrelin gene in 100 children with ARMs, 100 children with HSCR, and 100 healthy children (normal...
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