Article
Regulation of αA- and αB-crystallins via phosphorylation in cellular homeostasis.
Cellular and molecular life sciences : CMLS - 1 Nov 2015
Thornell Erin, Aquilina Andrew
Abstract excerpt
αA-Crystallin (αA) and αB-crystallin (αB) are small heat shock proteins responsible for the maintenance of transparency in the lens. In non-lenticular tissues, αB is involved in both maintenance of the cytoskeleton and suppression of neurodegeneration amongst other roles. Despite their importance in maintaining cellular health, modifications and mutations to αA and αB appear to play a role in disease states such...
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