Article
Linkage Analysis of Urine Arsenic Species Patterns in the Strong Heart Family Study.
Toxicological sciences : an official journal of the Society of Toxicology - 1 Nov 2015
Gribble Matthew O, Voruganti Venkata Saroja, Cole Shelley A, Haack Karin, Balakrishnan Poojitha, Laston Sandra L, Tellez-Plaza Maria, Francesconi Kevin A, Goessler Walter, Umans Jason G, Thomas Duncan C, Gilliland Frank, North Kari E, Franceschini Nora, Navas-Acien Ana
Abstract excerpt
Arsenic toxicokinetics are important for disease risks in exposed populations, but genetic determinants are not fully understood. We examined urine arsenic species patterns measured by HPLC-ICPMS among 2189 Strong Heart Study participants 18 years of age and older with data on ~400 genome-wide microsatellite markers spaced ~10 cM and arsenic speciation (683 participants from Arizona, 684 from Oklahoma, and 822...
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